Harold Ramis, the Chicago comedic writer, director and actor whose films “Stripes,” “Caddyshack,” “Animal House,” “Groundhog Day” and “Ghostbusters” are among the most beloved — and successful — of all time, has died. He was 69.

Ramis died overnight of complications from auto-immune inflammatory vasculitis, a rare disease that causes swelling of the blood vessels. He passed away peacefully, surrounded by family and friends at his Chicago-area home, where he returned to live in 1996 after 20 years in Los Angeles.

Despite Ramis’ passing, it looks like Ghostbusters 3 will go on without him.